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No evidence of effect modifications was observed for any subgroups, although the evidence was stronger for participants with high cardiovascular risk

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Their finding marked a decisive breakthrough because it challenged a long-standing belief that nerves controlled the secretion of digestive enzymes that had grown out of the work of Ivan Pavlov, the Russian physiologist who demonstrated that dogs can be conditioned to salivate by the sound of a bell (Rehfeld 2012)

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Shannon Arora, MD Chief Medical Officer, Arora Health Dr

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Inhibition by uric acid of free radicals that damage biological molecules

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